Hoehme Lab • Research group
Systems medicine • AI-based image analysis • Multiscale 3D liver models
Logos of funding organizations
Research interests

In general, we try to better understand the integrated physiological function of the human body in terms of structure and function of tissues, cells and proteins.
Currently, we are focussing on:

Image processing and analysis by artificial intelligence...
...and traditional methods to quantify and understand experimental and clinical images (histological 2D and 3D micrographs, CT, MRI, etc.). This includes the extraction of information not accessible to human analysis.

Multi-scale multi-species 3D modelling...
...of tissues and organ structures. We develop one of the world's most advanced 3D liver models and currently apply this technology also to other organs.

Construction of virtual biological tissues and organs ...
...based image data and expert knowledge linked by artificial intelligence. One aim of this new technology is to create patient-specific models for patient-specific diagnosis and treatment for example of hepatocellular cancer (HCC) in humans.
Collaborations
  • Leipzig University Hospital Leipzig, Germany >>>
  • Leibniz Research Centre for Working Environment and Human Factors (IfaDo) in Dortmund, Germany >>>
  • Leipzig Heart Center Leipzig, Germany >>>
  • French National Institute for Research in Computer Science and Control (INRIA) in Paris, France >>>
  • Helmholtz German Cancer Research Center (DKFZ) in Heidelberg, Germany >>>
  • Molecular hepatology, University Hospital Mannheim, University of Heidelberg in Mannheim, Germany >>>
  • Auckland Bioengineering Institute (ABI) in Auckland, New Zealand >>>
  • University College (UCL) in London, United Kingdom >>>
  • Chalmers University of Technology in Gothenburg, Sweden >>>
  • Fraunhofer Institute for Medical Image Computing (MEVIS) in Bremen,Germany >>>
  • Image and Signal Processing Group at the Department of Computer Science (IfI) University of Leipzig >>>
  • Bioinformatics Group at the Department of Computer Science, University of Leipzig >>>